Appropriate Usage of Antibiotics by Therapeutic Drug Monitoring
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چکیده
منابع مشابه
A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs
Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...
متن کاملTherapeutic drug monitoring--the appropriate use of drug level measurement in the care of the neonate.
Neonates and young infants are in a unique and dynamic pharmacokinetic state, in which they undergo relatively rapid maturational changes in drug absorption, distribution, metabolism, and excretion. In addition to these maturational changes, most drug pharmacokinetic studies in neonates show wide interindividual variability despite similar gestational and postnatal ages. Therapeutic drug monito...
متن کاملTherapeutic Drug Monitoring By Reverse Iontophoresis
Therapeutic molecules possessing distinct pharmacokinetic variation, narrow therapeutic index and concentration dependent therapeutic/adverse effects demand constant monitoring. The current methods for blood sampling are invasive and possess low patient compliance. Human skin, selective and effective membrane to chemical permeation, offers an alternative route for the extraction of endogenous m...
متن کاملTherapeutic drug monitoring
(Suggestions are based on Level III and IV evidence) • In both adults and children, C2 monitoring of CSA is superior to C0 as a predictor of AUC 0–4 and AUC 0–12. The C3 level is marginally superior to C2 for AUC 0–12. • Targeting AUC 0–4 levels for CSA of greater than 4400 ng/mL or C2 levels of greater than 1.5 by the end of the first week post transplant is associated with less acute rejectio...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2007
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.127.925